Globally, breast cancer is the most common type of cancer in women. The prevalence in Asian countries including India has been on the rise forming nearly one-third of all cancers detected in Indian women. As of today, there are nearly eight million women suffering from breast cancer. Certain inherited gene mutations like BRCA1, BRCA2 and PALB-2, greatly increase the risk of breast cancer. About 50 percent of breast cancer cases occur in women with no prior identifiable cause or hereditary basis. Some of the major factors implicated include age, obesity, alcohol and tobacco consumption, family history and postmenopausal hormone therapy among others. Over the years, it has been understood that breast cancer is a molecular disease with different genetic signatures. Thus, each patient needs a different approach to treatment and management based on many factors. One of the pivotal factors is the molecular and genetic profiling of the tumour cells. These prognostic factors determine the ...